Metaphase Arresting Solution (MAS) is a mixture of colchicine/vinblastine sulfate dissolved in PBS. Both compounds inhibit the formation of mitotic spindles and are used to increase the percentage of metaphase cells for chromosome studies. Vinblastine sulfate has been found to be more effective against bone marrows, difficult tumors and problematic tissues with low mitotic indexes, and where colchicine appears to be ineffective.

Makes 100mls of reagent